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This is a methodologically questionable approach and likely not possible without using double-fluorescent staining against an unaltered protein as standard (Schneider et al., 2004).
As there is no indication that these diverse problems have a common pathogenesis, the amalgamation of these outcomes for analysis is methodologically questionable.
Such an idiosyncrasy of both clinicians and regulatory agencies for the assessment of quality of life has favoured the use of several surrogate end points, potentially misleading and methodologically questionable.
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This narrowing of "the target group" is methodologically and ethically questionable.
Question questionable sources.
Medication effects may have influenced cognitive functioning; it would be methodologically ideal but ethically questionable to include a medication-naive group.
Considering that healthcare professionals have an ethical duty to palliate when a child is believed to be suffering at the end of life [ 12, 13], the lacuna of evidence-based care practices derived from PPC research with patients can be both ethically questionable and methodologically unsound [ 14].
The validation studies were methodologically weak and heterogeneous, making it questionable to compare the case definitions.
"Is this methodologically ingenious?
Methodologically, the process is specious.
Methodologically, the Tef is flawed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com