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Differences in target populations, age range, data collection, diagnostic and classification criteria, methodological study design, and a lower reliability of retrospective studies, may account for such controversial results.
The instrument development model combining qualitative and quantitative approaches was used as a methodological study design.
The investigators from Van de Rest et al. 2009 [ 36- 39] were the only investigators to adequately address all components of a high quality methodological study design.
In contrast, the remaining 9 studies were of a moderate-lower quality in their attention toward the methodological study design (1 study scoring 5/5, 6 scoring 3/5 and 3 scoring 2/5 according to the Jadad system).
28 Generation of statistical heterogeneity can be a consequence of clinical (participants, interventions and outcomes) and/or methodological (study design and risk of bias) diversity or due to random error (chance) alone.
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Here we present the results of a methodological study designed to examine the consistency of TCN-based deglaciation ages from a range of deglaciation landforms at a site in northern Norway.
Recommendations for future research, practice, and policy include more studies evaluating the unique impact of YPSS using rigorous methodological study designs, identifying developmentally appropriate training/supervision strategies and overall service costs and financing options, as well as distinguishing YPSS from other peer models with regard to certification and billing.
Study C is a methodological study designed to investigate the effects of study design, randomizing participants into three groups.
Future studies should aim to explore optimal methodological study designs that may facilitate the production of meaningful national estimates for meta-analysis.
More research using robust methodological study designs is possible and is needed, given the lack of evidence to support current policy.
The work can be generally divided into two types: (1) methodological studies designed to refine and improve the capabilities of AMS, and (2) studies which utilize radiogenic isotopes as geochronometers or as geochemical tracers.
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