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There are a number of methodological strengths of this study.
Important methodological strengths of the study include the large community-based sample and the prospective design.
Other methodological strengths of the study were the use of remote randomisation procedures and validated outcome measures of clinical relevance.
Several methodological strengths of our study suggest that the effect sizes are unbiased and perhaps even conservative.
With a community acting as a control and the methodological strengths of pre- and post-measures inherent in a time series design, this method is extremely robust.
The longitudinal population-based design and a high participation rate (93% of the total aged population) are major methodological strengths of this study.
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A methodological strength of our study is the prospective design and the long follow-up (12 18 months).
Understanding of the variables that will be considered for treatment guidelines can improve the methodological strength of studies and lead to recommendations for practice.
A methodological strength of the presented study is its prospective design, the large number of patients, classification of patients according ICHD-II, a comprehensive assessment including measurement of psychiatric comorbidity, implementation of a cross-sector computer documentation system and the long follow-up period of 12 months.
The methodological strength of the study by Strakowski et al. (2010) and the general consensus among studies provide strong evidence that impulsivity as measured by self-reports remains higher in euthymia than for healthy controls and may be a trait of those who experience BD.
Although the homogeneity of the patient population within our cohorts represents a methodological strength of the study, it may also be considered a potential weakness, as some real-world critically ill patients with FP would have not been included in our analyses.
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