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Interpretations going beyond this general statement, however, are neither appropriate nor intended due to methodological restrictions of the present study.
Within the methodological restrictions of the historical control design this study supports the introduction of 24-h intensivist cover in all intensive care units.
Within the methodological restrictions of the non-randomised design this study demonstrated an improvement in outcome in critically ill patients who receive neuroaxial blockade.
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A single search was used for both stages of the review with no methodological restrictions (for a sample of searches see Additional file 1).
We applied methodological restriction to be able to precisely analyse the coincidence of reproductive disorders and burnout: only reproductive disorders (high-risk pregnancies and miscarriages) of the last five years were taken into account.
Although numerous clinical reports support the neuroanatomical background for Ecstasy neurotoxicity in humans, published data are still incomplete and controversial, partly because of methodological restrictions [18].
There are methodological restrictions in data quality of primary studies, which have to be considered when interpreting the results.
That is, owing to methodological restrictions we changed the way of measurement respect to the aversive-only experiments.
We are aware that our results need to be interpreted cautiously because of some methodological restrictions.
Given the evidence that prescribing errors can arise as a result of multiple, interconnecting factors [ 92], the result is that few studies without most of the methodological restrictions described above are able to generate error accounts that reflect this phenomena [ 34, 40– 454 58, 58, 63, 88].
Considering the methodological restrictions, the findings should be interpreted primarily as explorative depictions of the characteristics and group differences of economic-civic competence.
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