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However, for a variety of conceptual and methodological reasons, such longitudinal research remains uncommon in the leadership domain.
The failure to detect cell-autonomous differences could be explained by various methodological reasons such as experimental design, the genes selected for read-out, or the nature of the stimuli and the sensitivity of the culture system to detect differences.
For methodological reasons, such segments have a low sharing of IBD signals and are prone to be false positives.
Several reasons could account for this discrepancy: First, methodological reasons such as different patients populations or different conditions under which patients completed the questionnaire.
This may be due to methodological reasons, such as population stratification (genetic heterogeneity, population history), inappropriate disease/trait definition, subject selection issues or chance findings.
Variation in reported results can also stem from methodological reasons, such as differences in sampling procedure, in sample size and hence statistical power or in the variables considered in the statistical analysis.
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Even the strikingly similar hybridisation and washing conditions should produce a comparable level of stringency, which would be one obvious methodological reason for such widespread disagreement in the presence/absence calling of genes.
There are some anatomical and methodological reasons which may contribute to explain such a phenomenon [39].
Such differences may have arisen from methodological reasons, as our study measured the relationship between leptin and endogenous endotoxin serum levels, as opposed to the effects on leptin as a result of exogenous endotoxin administration.
Nevertheless, for methodological reasons (small size, multiple interventions, non-randomized studies), the rare availability of such studies cannot be used to confirm that sodium bicarbonate is superior to other solutions used for vascular loading [163 167].
The trial was also cited for a variety of other reasons such as to support provider education or justify a statistical or methodological approach.
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