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Rigorous methodological quality includes, among other considerations, data quality and appropriate risk adjustment [ 15, 48].
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Methodological quality, including risk of bias of the studies, was evaluated using the PEDro Scale.
All these investigations were of high methodological quality (including rigorous sampling criteria in a community setting, use of structured interviews and application of DSM diagnostic criteria).
There was strong heterogeneity in the results due to inclusion of one old trial with poor methodological quality, including both children and adults and with a short course (<3 days) of hydrocortisone [39].
Much of the research on yoga has taken the form of preliminary studies or clinical trials of low methodological quality, including small sample sizes, inadequate blinding, lack of randomization, and high risk of bias.
Studies of lower methodological quality included refugees of various origin and host regions.
13 Methodological quality included allocation concealment, method of allocation to treatment, masking of outcome assessment and completeness of follow-up.
3 Our assessment of methodological quality included published trial protocols when such documents were cited in the original trial publications.
There was strong heterogeneity in the results due to inclusion of one old trial with poor methodological quality, including both children and adults and with a short course (<3 days) of hydrocortisone [ 39].
Small and large trials were compared in methodological qualities including sequence generating, blinding, allocation concealment, intention to treat and sample size calculation.
Of the included reviews, 60 (92%) had formally assessed the methodological quality of included studies.
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