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For every one of the pre-specified questions that concerned an issue associated with methodological quality, the responses were consistent with the practice of trialists in relation to the given issue being generally poor.
This is consistent with our findings that small studies had lower methodological quality compared with large trials.
Further research of better methodological quality and with more patient-relevant outcomes is needed".
"Vertical integration gives you high quality, consistent products with consistent genetics.
The methodological quality was assessed with the Jadad score.
Two independent reviews assessed methodological quality with the Jadad score.
Methodological quality was assessed with the Jadad scale.
Finally, to ensure high methodological quality, outcome measures with established reliability and validity have been selected.
Methodological quality was modest, with the vast majority of trials at high or unclear ROB.
The studies included are small in number and of variable methodological quality, with only one RCT.
Published negative studies should have the same rigour of methodological quality as studies with positive findings.
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