From a methodological perspective, an ideal COI study would clearly describe the perspective of analysis and, hence, the cost items (direct or indirect), cost collection procedure, discounting, quality of data, time frame of analysis, related comorbidities, and robust sensitivity analysis for all the assumptions.
From a methodological perspective, we propose a new econometric approach for the estimation of joint mixed models that include a multiple discrete choice outcome and a nominal discrete outcome, in addition to the count, binary/ordinal outcomes, and continuous outcomes considered in traditional structural equation models.
From a methodological perspective, it is a priority to balance e-based support across the control and experimental arms of the trial to ensure that potential improvement in clinical outcome is not confounded by differences in non-specific support and attention.
Some argue that the synchrony of social structure is a methodological perspective rather than an ontological claim.
From a methodological perspective, most studies used a prevalence-based epidemiological approach and a bottom up quantification of the costs method, both of which are considered the most accurate and consistent for the calculation of the burden of diabetes [ 25, 51].
From a methodological perspective, we accept that a 20 min walk has been represented using a straight-line distance from the central point of each postcode to create a buffer.
From a methodological perspective, the RCS is a newly developed instrument showing good validity and reliability [33].
From a methodological perspective, we have done a quasi-experimental design to eliminate the difference of institutions and used PSM to avoid the risks of selection bias based on doctors' characteristics in analyzing the effect of public reporting of medicine use information on rational drug use.
This is a reassuring result from a methodological perspective in that it supports a body of evidence that has emerged over the past decade that expression of the estrogen receptor gene is the strongest known factor that distinguishes etiologic subtypes of breast cancer.
