Suggestions(1)
Exact(4)
Our results suggest that even though the importance of qualitative research has been emphasized by several editorials and methodological papers in leading medical journals [10], [11], the proportion remains low.
The relevance of competing risks in medical research is highlighted by methodological papers in various medical fields.
However, we also invited a sub-group of people who carried out practical work in this area, but had not published methodological papers in the area, and whose work did not therefore contribute to the extracted list of items.
Criteria were reviewed by an international Delphi panel (n = 21), comprising authors who have published methodological papers in this area, and researchers who have been active in the study of sub-group analysis in RCTs.
Similar(56)
Two methodological papers investigated the increment in area under the receiver operating characteristic curve (AUC) when rare variants were added to models based on common variants using simulated data [ 11, 12].
We note that there are several excellent published methodological papers for researchers interested in conducting moderator analysis within a trial (e.g., [ 28]) The recommendations from this consensus are less conservative than several other well-publicised recommendations.
Nonetheless, despite being reported as early as the 1960s [ 3], included in the International Conference on Harmonisation (ICH) Good Clinical Practice (GCP) guidelines [ 4], and being clearly described in methodological papers specifically targeted at an orthopaedic audience [ 1], the ITT principle is not well known or uniformly used by orthopaedic investigators.
Unfortunately, the temporary literature especially of methodological papers discuss their results rarely in the framework of the hallmark pathways.
Four RCTs published methodological papers discussing challenges and solutions in recruitment, attrition and compliance (Higginson 2009; Jordhøy 2000; McMillan 2007; McWhinney 1994).
The data for 2000 and 2001 includes special issues of Statistics in Medicine and Statistical Methods in Medical Research on cluster randomisation, so there were a larger number of methodological papers than might be expected in those years.
Seven of the reviewed papers were methodological papers or a combination of a methodological paper applied in a specific case [31, 44, 50, 58, 78, 87, 108], while the remaining articles were primarily case studies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com