To date, some studies of renal biomarkers have been limited by methodological shortfalls (the methods used for measuring renal progression, the large number of biomarkers studied and the exclusion of certain groups of patients).
However its antibacterial effectiveness in the film form is controversial due to the methodological differences in test methods used.
Furthermore, good methodological standards recommend that methods used for sample size planning and for subsequent statistical analysis should be based on similar grounds.
Similarly, comparison of results may be hampered by methodological inconsistencies in the methods used to elicit a take-off response (escape response versus normal take-off), coupled with differences in the calculation of performance indicators.
In these cases, the valuation of descriptions should use the time trade off method in a representative sample of the UK population, with ' full health' as the upper anchor, to retain methodological consistency with the methods used to value the EQ 5D' [ 2].
The estimated age of the bottleneck for the pair of clades, 2.30 My, predates the estimated divergence time of all extant L. boeticus 1.5 Mya (Fig. 2B), suggesting methodological discrepancy between the methods used to date divergence times and those used to estimate time since expansion.
Methodological heterogeneity exists between sampling methods used to assess TSR.
Heterogeneity can be "clinical" (referring to characteristics of the population or the intervention), "methodological" (referring to differences in methods used in the different studies), or "statistical" (referring to differences in the direction or magnitude of the results).
The review has further shown that where such reviews do incorporate economics studies and data, methodological approaches vary considerably, and the methods used are not consistently reported.
In addition, the difference in published reports may be attributed to the numbers of samples tested, methodological differences, and the sensitivity of methods used, such as use of different primer sets.
