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In order to overcome methodological limitations for quantifying the impacts of emission abatement measures, economic evaluation techniques or even Integrated Assessment Methodologies (IAM) have been developed.
Notwithstanding cryptic nature of soil microbes and some methodological limitations for their study (Li et al. 2006), major changes in the composition and function of soil communities due to plant invasions have been reported with significant influence on soil C and nutrient dynamics (Bohlen 2006; Ehrenfeld 2003; Kourtev et al. 2002; Wolfe and Klironomos 2005; Yelenik et al. 2004).
Two methodological limitations for the interpretation of these results must be pointed out.
It could be argued that there are methodological limitations for interviewing participants on-line that go beyond the technical considerations.
Owing to methodological limitations, for example, cross-binding of drug and antidrug Ab in commonly used binding assays such as ELISA, levels are conventionally measured as trough levels.
Partly, such differences might be due to methodological limitations; for instance, BP measurements were practically absent in the mouse studies included in our meta-analysis.
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A potential methodological limitation for PWV is the distance measured externally on the body from the suprasternal notch to the femoral pulse.
Importantly, the observational studies may help to correct the methodological limitations of RCTs for the evaluation of complex public health interventions.
Therefore, allowing for methodological limitations of the quantification, the present data indicate that the mass dose effect is minimal within a tracer mass dose range of up to 50 μg.
Preliminary data suggest that overall and cancer mortality may be increased with TNF inhibitors; these findings should be confirmed in additional studies in view of methodological limitations of our study for this drug class.
14 15 The methodological limitations of using surveys for the assessment of nutritional protocols have been previously discussed in detail, 13 and it should be reiterated that while these surveys reflect the intention to treat of the personnel from the NICU who respond to the survey, they may not reflect the actual clinical practice within the unit.
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