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Background and methodological issues specific to each procedure are discussed.
The purpose of this publication was to improve the quality of such trials by increasing the awareness amongst investigators of the methodological issues specific to this particular illness.
The aim of this study was to describe methodological issues specific to conducting research with incarcerated vulnerable populations who have diabetes.
This article uses a geography of opportunity framework to highlight methodological issues specific for quantitative research examining neighborhoods and racial/ethnic health disparities, including study design, measurement, causation, interpretation, and implications for policy.
Although methodological issues specific to each experimental observation are discussed where appropriate, there are three issues that have a major impact on the interpretation of our results, and they will be discussed here.
The review also considers more general methodological issues specific to DIF analyses of HRQoL instruments, including the evaluation of DIF in short scales and the problems with interpreting DIF.
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In addition to conventional methodological issues, other specific issues may be relevant for healing research (Schlitz et al, 2003).
A key consideration for cross-cutting and specific methodological issues is that choices made enable confident interpretation of both positive and negative results.
Specific methodological issues addressed in this review, such as handling and reporting of missing PRO data, are particularly meaningful to ovarian cancer trials and trials of other disease groups.
The relationships between these several worlds raise not only specific methodological issues, but also epistemological questions like the need of overcoming technological determinism and the socio-material perspective (Fenwick, 2010).
In Table 3 the specific methodological issues are detailed.
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