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Another potentially relevant source of methodological heterogeneity is due to discrepancies in PT definitions, and, more in general, to the lack of a unique, systematic TMS protocol in the evaluation of PT in migraine.
We believe that, in this case, methodological heterogeneity is superior to statistical heterogeneity.
If clinical and methodological heterogeneity is present, we will perform subgroup analyses.
If considerable methodological heterogeneity is present, subgroup analyses will be performed through comparing the findings between studies of low and unclear or high risk of bias.
If considerable methodological heterogeneity is present, subgroup analyses will be performed by comparing the findings between studies of low, unclear, and high risk of bias.
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Methodological heterogeneity was assessed by comparing trial design factors (randomization concealment, blinding, follow-up loss, treatment type and co-interventions).
Methodological heterogeneity was assessed by comparing the differences among the adjusted models.
Much of the methodological heterogeneity was due to the varied definitions of disability among these studies.
Provided we thought it clinically appropriate, and no important clinical and methodological heterogeneity was found, we summarized results in a meta-analysis.
As a result, no significant clinical heterogeneity or methodological heterogeneity was found.
6 8 As with most network meta-analyses, methodological heterogeneity was present.
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