Fifteen trials explicitly reported having used the review as a basis for the choice of the primary reference treatment as a comparator (of which one criticised the fact that the studies included in the review were too disparate and that they had methodological gaps, and therefore they chose to repeat the comparison).
To fill this methodological gap we have designed and implemented ProtNet a computer model that captures the discrete and stochastic nature of protein interactions [ 12].
Unfortunately, previous studies (e.g., Fitzgerald 2005; Geisinger 1994; Lokan and Fleming 2003) proved to be of limited assistance as they revealed a research and methodological gap concerning the adaptation of computer-based tests, particularly in VET.
The absence of tools to reliably assess the quality of patients' reported goals and action plans creates a critical methodological gap for self-management research, and ultimately, for chronic care outcomes.
The proposed approach allows for bridging a methodological gap between sequence-based bioinformatics and molecular dynamics simulations: molecular interactions can be modeled based on physio-chemical model in a highly parallelizable and high-throughput-ready fashion.
The result of this study bridges the methodological gap between the chromosome banding and molecular biology techniques for genetic diagnostics through single-molecule characterization and biochemical label-free imaging of chromosome architecture at subcellular resolution.
This paper fills this methodological gap by offering clear support in the design and execution of a study on business relationships and networks using critical realism as ontology.
Although notable methodological developments have been realized when using Altman's (1968) bankruptcy prediction model as a starting point, a methodological gap remains in accurately predicting turnaround, linking content to process and context.
The method is driven to bridge the methodological gap to design a point clustering method to maintain both origin destination direction and ranking information for those data.
This paper addresses a methodological gap in the application of CTT techniques, such as PCA, in instrument development and reports a novel and reproducible method for mapping between theoretical and empirical factor structures to label empirically-derived factors.
