Sentence examples for methodological flaws including from inspiring English sources

Deviations from HWE in the control group may indicate significant methodological flaws including selection bias, population stratification and genotyping errors [57].

Bias is caused by methodological flaws including the population under study, the choice of inadequate comparators or of their dosage, the adoption of surrogate or composite endpoints, the decision to publish mainly positive findings or to overlook some safety concerns, etc.

Most studies to date linking healthcare workers' intention to their behavior have recognized methodological flaws including lack of experimental design, poor methods in measuring behavior, poor matching of the context of the intention with the behavior measured, and poor reporting of studies [27], [28].

However, the effect size of these clinical studies was underestimated because of methodological flaws, including inadequate statistical analysis, a failure to describe differences in baseline stroke severity, and an inadequate assessment period [ 11, 12].

122– 124 However, the results of most previous pharmacogenetic studies focused on oxaliplatin were limited, and with several methodological flaws, including small sample size, retrospective study design, and the implementation of a post-hoc analysis of oncology-based databases of different, not pre-planned sizes.

Methodological flaws included the lack of blinding, the lack of intention-to-treat analyses, inadequate allocation concealment, the unclear definition of primary outcomes, and high drop-out rates.

These studies suffered from methodological flaws and included a heterogeneous population of ICU patients, including those with sepsis.

Nevertheless, it is important to emphasize that most of these RCTs have various methodological flaws and included small samples with inadequate power to assess the risk of adverse effects.

This study has a number of methodological flaws limiting generalisability, including absence of a control solution, and no blinding in acquisition of key study metrics (GCS).

In addition, the methodological flaws of the included trials and inconsistent findings disable us to recommend any specific CHM for recurrent miscarriage.

The first review was published in 2010, 12 which could not draw a conclusion due to the serious methodological flaws of the included studies.