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That might be due to the methodological disadvantages of self-reported questionnaires to assess physical activity [34].
However, it is possible that these negative results are caused by the methodological disadvantages of previous analyses that prevented the quantitative and sensitive detection of important evolutionary differences between TM and EM regions.
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In turn, the larger MAE and RMSE values in the study by Kay [ 29] are probably attributable to the methodological disadvantage of coping with the presence of significant ceiling effects.
However, one methodological disadvantage of the quasi-experimental design is that students are not randomly assigned to experimental and control groups, as they are in a true experimental design (hence its name, "quasi-experimental").
Whilst this is a clinical benefit, it is also a recognised methodological disadvantage of the crossover design, in which behaviour in the first period cannot be nullified for period 2. In this case, there was possibly a behavioural component, either by influences of the investigator, the patients themselves, their parents or a combination of these, reducing the number of wet nights over time.
Furthermore, this approach has methodological disadvantages.
Fourthly, using a Likert-scale has several methodological disadvantages [ 35].
In spite of these applications, MSs associated with interspersed repeats not only distort estimates of the genomic distribution of MSs useful for genome mapping [ 27], but also entail some methodological disadvantages.
Apart from the advantages of the combination, however, we also need to mention one methodological disadvantage.
Consequently, all historic approaches have a methodological disadvantage in common: Besides our case study calculations other research stresses the non-linear rates change of deforestation for many countries, often moving towards forest transitions [13, 41].
Consequently, all historic approaches have a methodological disadvantage in common: Besides our case study calculations other research stresses the non-linear rates change of deforestation for many countries, often moving towards forest transitions [ 13, 41].
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