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3, Since the quantification of the intensity of contacts is characterized by methodological difficulties (the number of contacts does not always turn into quality), I used the scores, based on available information: 0 point no ties 1 point connection exists; however, financial information is not provided or the total annual turnover of affiliated companies is less than ten million RUB.
Given the background of methodological difficulties, the findings of our study should be interpreted with caution.
As suicide research has to deal with specific methodological difficulties the design and development of study protocols needs to be cautious.
None of the HTA agencies included intangible costs in the denominator, reflecting that this cost type is seldom used because of methodological difficulties (the same cost influences the numerator as well as the denominator in the analysis).
For cultural reasons and because of methodological difficulties, the association between type 2 diabetes and sexual function in women has been studied in fewer objective studies than the effects of diabetes on sexual function in men [ 4].
Despite conceptual and methodological difficulties, the assessment of (HRQoL) can assist in caring for chronically ill patients and the most common measuring approach is using descriptive psychometric instruments that describe health status in a number of different areas.
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To avoid such a methodological difficulty, the proposed models still use slacks for those outputs.
20 This may be a reflection of the ongoing debate surrounding the definition of competence and 'skill', 6 the methodological difficulties surrounding the monitoring and measurement of competence, 24 and the significant expenditure of time and resource required to collect and analyse competence data.
Due to methodological difficulties in the determination of the aromatase protein, COX-2, an enzyme involved in the synthesis of aromatase, has been suggested as a surrogate marker for aromatase expression.
The modeling and estimate of the fixed asset tax for RE, however, poses substantial methodological difficulties, as the depreciation curve of the RE investment has to be taken into account.
The results of this study reveal the methodological difficulties associated with the assessment of the consumption of antibiotics by neonates.
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