Sentence examples for methodological difficulties of from inspiring English sources

Diagnosis of pancreatic exocrine insufficiency (PEI) is hindered by methodological difficulties of pancreatic function tests.

Previous studies have demonstrated the feasibility of engineering brewer's yeast by incorporation of heterologous genes13,28,29; however, the scope and commercial relevance of these efforts have been limited, in part due to methodological difficulties of incorporating an array of large, genetically stable DNA constructs into industrial yeasts.

Second, it ensures that a study does not focus exclusively on the characteristics that the individual brings to the table to the exclusion of the structural opportunities and barriers that they face – notwithstanding the methodological difficulties of so doing.

This contrasts with a number of methodological difficulties of obtaining representative measures of species-specific testis size, which is largely due to the fact that testes show strong seasonal and age-dependent size variation in birds [5], [61], [62].

However, some methodological difficulties of the study need to be discussed.

On the other hand, ethical and methodological difficulties of randomised controlled trials (RCT) on coercive interventions have only recently been addressed [ 22].

We used the latest developments in the application of the magnetic resonance geophysical method to confront the methodological difficulty of quantifying groundwater storage.

Conceptualising integration in this way nevertheless requires an attempt to identify the full range of effectors that may impact significantly (often in gendered ways) on integration processes, or at least to acknowledge those that have not been considered because of the methodological difficulty of so doing.

The neural invariances, in terms of the locations and activation amplitudes of common diagnostic voxels, emerged despite the methodological difficulty of normalizing the morphological differences among participants.

An important methodological difficulty of the present study is the retrospective nature of data collection.

These standards, however, are barely established in psychotherapy, which may be due to the lack of evidence-based guidelines, the methodological difficulty of comparative research and the diversity of psychotherapeutic schools.