Sentence examples for methodological difficulties are from inspiring English sources
Suppose, however, that Moody-Adams is right, and the methodological difficulties are insurmountable.
These methodological difficulties are most especially seen in the information technology development arena where current paradigms continue to adhere to a myopic view of technology as it relates to its cultural context.
The example of GGA1 also shows the limitations of the models since methodological difficulties are arising with several QTL on the same linkage group fitting different models and possibly in interaction.
Similar methodological difficulties are encountered both in MCIDs and PASSs: both approaches lead to a loss of power compared with the population-level mean difference, both approaches depend on population and contextual characteristics and there is no clear consensus on the optimal statistical approach.
The root-derived carbon (C) input to the soil, whose quantification is often neglected because of methodological difficulties, is considered a crucial C flux for soil C dynamics and net ecosystem productivity (NEP) studies.
When estimating the effects of a new connection in terms of FDIs, one major methodological difficulty is that other unobserved factors may account for the changes, rather than the existence of the new route.
It is clear that there is a need for rigorous research in this area and that there are methodological difficulties to be overcome [ 68, 69].
Although quantification of apoptosis, and so comparison between tumour types and studies, is beset with methodological difficulties, there is evidence that oligodendrogliomas show higher levels of apoptosis than other brain tumours of comparative WHO grade [ 15, 28].
Despite methodological difficulties, there is now convincing evidence that such multiplier effects are empirically important (Bertrand et al.2000; Ichino and Maggi, 2000; Aizer and Currie, 2004; Hesselius et al.2009; Åslund and Fredriksson, 2009; Rege et al.2012; Markussen and Røed, 2012).
As a result of these methodological difficulties, it is sometimes simply assumed that the RH2aα and RH2aβ paralogs are sufficiently similar to justify treating them equivalently [ 45, 46].
Such methodological difficulties can be overcome in trials of laser acupuncture as it is possible to successfully blind both participants and clinicians by using specially designed laser machines [ 24].
