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In addition, there were methodological differences concerning infection and cultivation procedures as well as assays used.
This could be partly due to methodological differences concerning the estimation of personnel costs.
This might reflect different hormone concentrations in urine versus blood, differences in assay sensitivity, or other methodological differences concerning sample collection.
This controversy regarding the staining patterns of uPA system components in PCa or BPH tissues may be related to methodological differences concerning mRNA hybridization or the specificity of antibodies used for IHC [ 25].
Although there is general agreement that physical status before trauma influences outcome, an overall quantification of the effect has been difficult to achieve because of major methodological differences concerning grading of disease.
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A comparison of data processing, however, identified methodological differences between the centres concerning the framing of PET data, data reconstruction, tumour delineation and ROI definition to evaluate tracer kinetics in the tumour.
Wide variations in reported incidence depend on methodological differences between the studies, mainly concerning the implementation of delirium diagnostic scales and methods [ 5, 6] and study of population characteristics.
However, methodological differences in the design of studies concerning canine scent detection make it difficult to directly compare and to evaluate their results.
Although previous literature clearly suggests that heterogeneity in prevalence rates of the disorder is associated with methodological differences among studies [ 7], there are yet concerns that ADHD prevalence might be exaggerated in some environments [ 8].
The discrepancies between the studies concerning significant association with particular forms of vessel involvement might be attributed to the differences in the clinical profile of patients involved in different studies as well as to methodological differences in clinical assessments.
I appreciate that methodological differences complicate comparisons, but the fact that there is not a close alignment of the animal and human studies remains concerning to me.
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