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We summarize here the impressive methodological developments of the last years to model and analyze the metabolism of P. pastoris, and to engineer its genome and metabolic pathways.
The main disadvantage is that the developments in metaproteomics would still be linked to growth, achievements and methodological developments of metagenomics.
Further conceptual and methodological developments of these tools are needed for the integration of various data types across the multiple levels of organization and time frames that are characteristic of human development, physiology and disease.
A promising avenue is the new methodological developments of spinal cord imaging that has the advantage to investigate the two motor system components that are involved in ALS, that is, the lower and upper motor neuron.
The recent availability of huge amount of sequence data for a wide range of organisms, together with new methodological developments of in silico mining of microsatellites, have tremendously increased the characterization of these markers [ 5], and will certainly catalyze the study of genomic distribution of microsatellites in eukaryotes.
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Section "Ontology-based methodological development of MAS" develops this into a sketch of an iterative ontology-based methodology and describes how this can be adapted to a given specific context.
The model for the survey, developed jointly by researchers and planners, is composed of four steps: methodological development of data collection; national survey and regional ranking; national analysis; and applications.
Except for A.M.H., all authors listed to J.R.W. were joint project Principal Investigators and contributed to the conceptual and methodological development of the project and analysis of data.
The work identifies a need for a methodological development of Life Cycle Process Design (LCPD).
The findings of this paper serve as basis for the methodological development of LCPD.
Further, the study delivered a methodological development of the dynamic SCB test, which potentially advances the current state-of-the-art pertinent to fatigue evaluation of asphalt mixtures.
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