The remaining 9.9%% of the documents are either concerned with methodological developments or the calculated substances are not a major concern of the document.
Methodological developments like "pre-phasing" (which we address in the Discussion) can alleviate this concern by speeding up imputation, but existing methods still need substantial computing power to handle reference sets with thousands of haplotypes.
It emphasizes on the methodological developments.
These studies showed that more methodological developments are required.
AO: Contributed to study plan and methodological developments.
Methodological developments are key to the analysis of transmembrane proteins.
The estimation of CVD risk is a dynamic research field and there are a number of unresolved methodological issues concerning the development, validation and comparison of risk scores.
Methodological issues concerning the specification of indicators and development of monitoring systems were addressed, as well as the current scarcity of global monitoring data in this field.
In addition, there were methodological differences concerning infection and cultivation procedures as well as assays used.
Major methodological problems concerning the measurement of physical activity are discussed.
