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This finding is different from data reported by others [13] but this might be related to differences in methodological determination of protein dosage, or a higher dispersion of GAA sizes (2 21 in our study and 7 18 in [13] for GAA1; 2–24 in our sample and 8 26 in [13] for GAA2) with possible ethnic differences.
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Importantly, our approach represents a significant methodological advancement in determination of drug uptake for single-cell pharmacology.
In conclusion, the paper provides a useful methodological contribution to the determination of dynamic effects caused by the interaction vehicle-road pavement, by evaluating the entity of the dynamic overload induced by surface irregularities.
Schueremans et al.'s [17] 3 stage methodological approach for the determination of compatibility utilised pre-investigation, materials specification and post application re-evaluation of performance.
Methodological problems (imprecision in determination of VO2, assessment of global VO2 instead of regional VO2, poor correlation between systemic oxygenation parameters, and oxygenation in the microcirculation [13]) also may contribute to these discrepancies [31].
The main aim of this paper is the establishment of the most suitable methodological combination for the determination of the badland denudation rate, which is the gully rock wall retreat rate.
Due to methodological difficulties in the determination of the aromatase protein, COX-2, an enzyme involved in the synthesis of aromatase, has been suggested as a surrogate marker for aromatase expression.
We are well aware of methodological advances in the determination of free thyroid hormones based on the technique of isotope dilution tandem mass spectrometry [ 22- 29] which correlates better with equilibrium dialysis procedures [ 30].
Methodological problems (imprecision in determination of VO2, assessment of global VO2 instead of regional VO2, poor correlation between systemic oxygenation parameters, and oxygenation in the microcirculation [ 13]) also may contribute to these discrepancies [ 31].
For the extraction of anchor-based methods studies used to estimate MIDs, a team of methodologists familiar with MID methods will use standard thematic analysis techniques 14 to abstract concepts related to the methodological quality of MID determinations until reaching saturation.
From this vantage point, general covariance is but the most recent refinement of the methodological principle of "unity of determination" governing the constitution of objects of physical knowledge, completing the transposition in physics from concepts of substance into functional and relational concepts.
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CEO of Professional Science Editing for Scientists @ prosciediting.com