Sentence examples for methodological deficiencies were from inspiring English sources
Any studies that were found to have methodological deficiencies were excluded at this stage.
Several independent meta-analyses have confirmed a better outcome in patients receiving EEN compared with patients not receiving EEN, even though methodological deficiencies were found for some studies [ 126].
Methodological deficiencies are defined as an inappropriate methodology of the indirect comparison, as for example heterogeneity of study results within MTC, non-similarity of studies, inconsistencies of outcomes of comparisons.
Usually methodological deficiencies are examined critically in case results are not in line with the expectations of the researcher or reader, but when results meet the expectations, methodological strengths and weaknesses will receive less attention.
However, the most frequent methodological deficiency is still the application of a comparator differing from the appropriate comparator defined by G-BA.
These studies suffer from major methodological deficiencies and were of sub-optimal quality, limiting their validity and reliability.
The studies included in this review suffer from major methodological deficiencies and are of sub-optimal quality, limiting their validity and reliability for policy-making in the country.
Nonetheless certain deficiencies were soon noted.
In spite of these methodological deficiencies, it has been shown that high SPF is a property that is related to poor prognosis for many tumours (Kallioniemi et al, 1987).
[23] [25] While some of the methodological deficiencies we described were linked to the specific peculiarities of '-omics' based research, other important aspects -which have long been considered fundamental in traditional diagnostic research, such as the description of the index test and test reproducibility- are being overlooked in '-omics' research.
The methodological deficiencies that must be understood in order to realistically interpret our findings are summarised in Table 2, where we have identified possible pitfalls in research on rates of evidence-based practice.
