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The starting point of this approach is the notion that much of human reasoning, including probabilistic and causal reasoning as well as problem solving takes place through mental modeling rather than through the application of logic or methodological criteria to a set of propositions (Johnson-Laird 1983; Magnani et al. 1999; Magnani and Nersessian 2002).
First, it was restricted to randomized controlled trials that met predetermined methodological criteria to minimize the potential for bias.
Also, we applied strict methodological criteria to functional outcome evaluation by only including hips that had an event-free follow-up of at least 2 years.
Thus, there is still a need to develop methodological criteria to guide meta-analysis of moderators, including statistical guidance for the analysis of interactions.
There is consensus from a group of 21 international experts that methodological criteria to assess moderators within systematic reviews of RCTs is both timely and necessary.
We therefore completed a systematic review and meta-analysis of only those studies that met predetermined methodological criteria to estimate the effect of OADs on A1C levels.
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At the same time Karl Popper was defending a methodological criterion to demarcate science from metaphysics based on the falsifiability of all genuinely scientific propositions.
For our secondary objective (to investigate variations in adherence to reporting and methodological criteria according to study or journal characteristics) we repeated the above analyses after classifying trial setting as clinical versus non-clinical and after classifying journals as higher (above the median) versus lower impact factors and as general medical journals versus other.
The aim was to use these guidelines and other methodological criteria [16] [18] to produce a systematic review that is comprehensive and summarizes the data collected (see PRISMA Checklist S1).
Two reviewers independently abstracted 14 criteria related to quality of reporting and four methodological criteria specific to cluster randomised trials.
In order to derive such descriptive knowledge from available data, specific methodological criteria have to be met (e.g., representativeness).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com