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The study highlights how driving simulators can be used to overcome methodological constraints encountered in real-world evaluations of this type.
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If implementation is impossible, as it sometimes is because of the constraints encountered, new plans must be formulated.
Our developed algorithm can effectively handle constraints encountered in chemical engineering optimization problems.
Budget constraints encountered during construction meant that the bridges were structurally quite weak.
In contrast, the epistatic constraints encountered during PchB divergence allowed for the persistence of a promiscuous chorismate mutase function.
The reasons and implications of this choice are discussed further (see "Methodological constraints").
Conclusions are limited by methodological constraints.
Another telling factor that we could not include, given our methodological constraints, was the existence of domestic partner registries.
This, however, is an often-understudied parameter due to methodological constraints.
Multiple methodological constraints and sources of variance have limited the resolution of electrophysiological experiments.
In spite of methodological constraints, there is a demand for intersectoral assessments, especially in health sector reform.
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