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A number of methodological concerns have been raised about studies examining the validity of the HBM.
Patient-specific quality of life indices show great potential, but certain conceptual and methodological concerns have yet to be fully addressed.
Several methodological concerns have been identified in our review.
These methodological concerns have raised questions regarding the value of such a trial (Gollub and Stein, 2012; Morrison and Nanda, 2012; Ralph et al., 2013, 2014; Cates, 2014), and the investigators acknowledge the threat to the quality of data generated.
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Findings from lifestyle intervention programs in school settings have been limited by methodological concerns and have primarily focused on basic measures of obesity, such as body mass index.
But, in addition to the methodological concerns people have raised about the N.C.V.S., the survey defines "college women" to include any woman between eighteen and twenty-four who is enrolled, full or part time, in any post-secondary institution.
It is beyond the scope of this brief note to address the methodological concerns that have been raised regarding the design of that study.
Methodological difficulties as well as reproducibility concerns have until now prevented the usage of EGFR GCN as a predictive marker in the clinic.
Numerous concerns have been voiced regarding the methodological soundness of these meta-analyses.
A secondary, methodological concern here has to do with the terminological ambiguity of 'expectation'expectation
We identified important methodological concerns which could have resulted in selection bias and exposure misclassification and contributed to null findings and biased associations.
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