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While significant methodological challenges exist, the approach we detail can provide the holistic view of energy and ecosystem services interactions required to inform the future of global energy policy.
In studying OA, several methodological challenges exist that can hamper our ability to identify pertinent relationships.
The IPD approach offers many opportunities but methodological challenges exist, including: unavailability of requested IPD, missing patient data and predictors, and between-study heterogeneity in methods of measurement, outcome definitions and predictor effects.
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A methodological challenge exists because of small sample sizes, which are a consequence of the moderate climate in the region, and, in the case of critical development stages, of the fine-tuned and specifically adapted production systems.
An Institute of Medicine report on clinical guidelines recommended that information on cost implications be incorporated into guidelines; however, the report acknowledged that major methodological and practical challenges exist to implement this recommendation.
In short, the potential for using the Internet in this field, to improve the application of cost utility analyses and address some of the important methodological challenges that exist in preference measurement, is only beginning to be exploited.
However, when involving users in the comparison of search systems, methodological challenges still exist as researchers are pondering on how to handle the variability that human participants bring to the comparisons.
While this study supports the application of the EQ-5D-3L™ for injured children, some methodological challenges do exist.
Despite this progress, many more challenges exist.
However, sizable challenges exist.
These challenges exist throughout corporate America.
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CEO of Professional Science Editing for Scientists @ prosciediting.com