Sentence examples for methodological barriers from inspiring English sources

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While a placebo-controlled trial in vaccine refusers may be considered, such a trial is unlikely to meet substantial methodological barriers regarding trial size and generalizability.

Whilst adaptive planning has gained increasing attention, the uptake of such methods has been relatively limited compared to the scale of the adaptation challenge due to institutional, financial and methodological barriers.

In spite of the progress made over the years, important methodological barriers remain in the statistical analysis of crash data and this, along with the availability of many new data sources, present safety researchers with formidable future challenges, but also exciting future opportunities.

Methodological barriers affected 23percentt of respondents.

Several methodological barriers and limitations have been identified that require addressing through future research.

It addresses methodological barriers that limit the available data and evaluates the adequacy of the data for risk assessment.

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Despite of the satisfactory psychometric properties of the Brazilian Portuguese MIA version, its extension is still a methodological barrier in many research contexts, such as with elderly samples, individuals with cognitive dysfunctions, or in studies with extensive experimental designs.

Finally, a methodological barrier is that it is argued that there are no clear existing methods for incorporating evidence on patient preferences in the decision- or development process [ 51].

27 28 29 Ironically, the major methodological barrier to more individualised therapies is not a paucity of predictors of outcomes and effects, it is that patients have so many attributes that potentially affect risk and response to treatment that subgroup analysis is statistically unmanageable.

There are ethical, methodological and organizational barriers that explain this separation.

The implementation of standardized QL measurement in clinical practice is proving to be difficult due to practical, methodological and conceptual barriers (Deyo and Patrick, 1989; McHorney and Tarlov, 1995).

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