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Details of the methodological assessment are shown in Fig. 2.
The test threshold of presepsin of diagnosing sepsis ranged from 317 to 729 pg/ml.> -wrap-foot> intensivesive care unit, ED emergency department, PR prospective recruitment, CR consecutive recruitment, NA not available, ACCP/SCCM American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Details of the methodological assessment are shown in Fig. 2.
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There is currently no validated gold standard or single recommended instrument for methodological assessment of risk factor studies, so a combined methodological assessment was developed for this review and tailored to assess the specific areas of risk factor studies which were considered to be important.
Study methodological assessment was evaluated using the PEDro score.
Data extraction and methodological assessment were conducted by two reviewers independently.
A three-stage inclusion process consisting of initial sifting, checking full-text papers on inclusion criteria, and methodological assessment, was performed independently by two reviewers.
The methodological assessment was done by one researcher [PM] and 50% of the references were also checked independently by a second reviewer [AF, WD] (in this case the mean of the two scores was computed).
The search strategy was completed by MF, data extraction, analysis and methodological assessments were made by MF, DB and JS.
In Table 1 the results of the methodological quality assessment are described.
The results of methodological quality assessment are shown in supplementary material Fig. S6.
The results of the methodological quality assessment are presented in table 1.
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CEO of Professional Science Editing for Scientists @ prosciediting.com