We investigate the key features of such analyses as regards their analytical and methodological approach and we identify emerging lessons from PES practice, leading to a new suggested research agenda.
All included studies were judged to be clinically and methodological heterogeneous, and we decided to preclude meta-analysis and describe findings for each study individually.
We introduce a new task format to overcome these methodological issues, and we provide an organization index (OI) to assess subjective organization of information objectively and automatically.
This is true for many methodological criteria and we urge meta-analysts to give explicit details of the protocol they employed in making their decisions.
The synthesis of qualitative research is an expanding and evolving methodological area and we would value feedback from all stakeholders for the continued development and extension of the ENTREQ statement in terms of content, clarity and feasibility.
The synthesis of qualitative research is an expanding and evolving methodological area and we would value feedback from all stakeholders for the continued development and extension of the ENTREQ statement.
We made sure that such information was immediately available to the reader as a methodological point, and we kept it short in the discussion to focus on positive findings.
However, few studies are randomized trials, most have significant methodological limitations, and we are not aware of any trials that have evaluated the impact of TC on both BMD and postural control in osteopenic women [ 14, 15].
We sequenced a 853 bp mtDNA fragment in 88 individuals to an average coverage of 49334-fold, using quality control filtering and triplicate PCR analysis to reduce any methodological bias, and we detected 119 heteroplasmic positions with a minor allele frequency ≥ 0.2%.
First of all, the trial was conducted with an overall high level of methodological quality and we assessed the validity of the trial results according to the procedure proposed by Jakobsen et al 34, including adjusting the thresholds for significance according to the number of randomised participants and the planned sample size.
