Within the proposed methodological framework and disease investigated, the systems-level analysis is promising because it can detect potentially novel genes beyond the traditional differential gene expression analysis.
Meta-analysis was not attempted due to heterogeneity; the studies differed considerably in methodological design, risk factor assessment and disease groupings.
d Part of the Public Health Network, providing methodological support for health protection and disease control, environmental health, occupational health, and food and nutrition policy for regional inspectorates, regulatory bodies, and laboratories.
Besides the number of patients and disease stage, these studies differ in some methodological aspects.
This study should provide the methodological basis for future studies of tissue RAS in human physiology and disease.
This methodological issue may have contributed to the discrepancies regarding circulating HMGB1 and disease activity between the two studies.
We found HCW respondents had high expectations for the methodological quality of AR, and the translation of findings from AR to human responses to drugs and disease.
Diverse methodological approaches for measuring health status, disease occurrence, and the association between risk factors and health outcomes will be presented via classic and contemporary studies of chronic and infectious illness and disease outbreaks.
CARTA is neither disease-focused nor discipline-specific, but brings together diverse methodological and disciplinary approaches to context-specific health and development issues facing Africa.
Factors related to the methodological quality, target disease, publication year, and study design were determined by multiple logistic regression analysis (Table 2).
