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But these methodological advances were gained at the expense of coverage.
In formulating the items of the GRIPS Statement, these methodological advances were anticipated.
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Nevertheless, further methodological advances are needed to obtain truly routine and widely available in situ14C analysis.
Methodological advances are required to effectively analyze such large amounts of data.
First, however, technological and methodological advances are necessary for the blood transcriptome research field to move beyond the proof of principle stage.
One of the promising recent methodological advances is the introduction of a site-heterogeneous non-parametric mixture CAT model that allows for site-specific features of protein evolution [ 43].
Thus, we see the methods described here as likely to be most applicable to targets that cannot easily or robustly be characterised using current prevailing method (for the reasons described earlier, see Sections 3.4 and 4.2) These methodological advances are likely to make chemical denaturant titrations more relevant to pharmaceutical research.
Not only has a methodological advance been demonstrated, but also the results hold possible medical significance.
This methodological advance is in contrast to other methods that consider only identical annotations or are based on GO enrichment computations.
An important methodological advance was made by Dehal and Boore [ 10], who used an ingenious approach of mapping 2R paralogons by first identifying descendants of gene duplications mapping to the base of vertebrates by phylogenetic timing.
Therefore, before additional methodological advances can be made, a logical first step is to collate and understand the patterns of reported peer-reviewed claims of reassortment.
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