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However, these approaches are inherently complex, in terms of regulatory and methodologic implementation, and present a high cost.
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The specific research question will dictate the choice of study design and methodologic considerations for study implementation.
It is likely that practical, medical, methodologic, and financial factors will prevent implementation of the recommendation in the majority of clinical settings.
On the imaging side, key methodologic advances of this work include implementation of a simple, versatile, and efficient approach to multiparametric mapping, using a single detector.
The methodologic and ethical advantages of this method are described, and potential barriers to the method's implementation are addressed.
It will negate that methodologic difference".
Piantadosi, S. Clinical Trials: A Methodologic Perspective.
Design: Cross-sectional methodologic study.
The $2.6 Billion Pill - Methodologic and Policy Considerations.
However, methodologic bias can overestimate benefit.
Data Extraction: Authors reviewed design and other methodologic issues.
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