While constraints regarding data availability and the need to maximize sample size will always be an issue, the question of which SEP measure to use is an important methodologic concern, and merits more consideration by researchers in the field.
One methodologic concern with the ART-CC data was that it only included data from the time antiretroviral therapy was initiated, and thus did not have data regarding morbidity and mortality during the pre-therapy untreated phase.
There are several methodologic concerns in studies of this nature.
Whether or not IG itself causes DPN (and of which kind), retinopathy, or nephropathy has been studied, but the results have been questioned because of methodologic concerns and discordant results (5, 8, 16, 18, 21– 21).
Importantly, prospective follow-up of cancer cases should be considered to address some of the methodologic concerns noted in this article, such as cancer-related weight loss and OC concentrations, in addition to exploring the effects of OC concentrations on survival.
His methodologic research is funded by various NIH statistical grants starting from 2003.
This may allow for improved prediction of mortality for patient populations similar to the reference database, although the subjective versus objective methodologic debate is likely to continue.
Previous studies have shown that methodologic information is often inadequately described in RCT protocols [20] [25].
Hence, the first methodologic issue is the choice of an appropriate exposure marker for MeHg.
One methodologic issue is the "performance confound", frequently discussed in imaging research, but also relevant here.
