Sentence examples for methodical problems of from inspiring English sources

This lack of relation could be due to methodical problems of PPAR γ detection in archived tumor samples and in the complexity of TZD action.

They are concerned that our findings of an unexpected high percentage of heterogeneity reflect methodical problems of mutation detection rather than tumour biology.

Methodical problems in research of rare diseases should not lead to negligence.

Because of an often very small sample size, because of inconsistent results and because of methodical problems in the monitoring techniques used in these studies, however, it is not possible to provide clear recommendations concerning the use of catecholamines in sepsis.

The presence of high amounts of proteases causes methodical problems [ 12], resulting in a contribution of proteolytic fragments to the observed protein spots.

Methodical problems, mainly the bad quality of older tissue specimens, reduced the number of cases that could be evaluated by up to 30%.

In such measurements some methodical problems arise, which bring about inconsistency of the data samples combined from different sources; this work describes the problems at hand and proposes solutions on how to eliminate the inconsistencies.

In view of the many methodical problems which come up upon selecting a threshold, even for retinopathy, we would suggest a more pragmatic decision.

This is due to the limited knowledge about the course of trauma-related symptoms and the methodical problems in longitudinal studies to address the same construct in different age groups with other psychometric methods.

Besides methodical problems, this might be due to the relatively high costs and the complexity of these diagnostic tools (Yoo and Lee 2008; Mach et al. 2009; Fenollar et al. 2006; van Veen et al. 2010).

Therefore, it is necessary to identify and apply a methodical problem solving approach to overcome these situations.