We describe here the methodical, cooperative comparison, in vitro (in DMD cells) and in vivo (in a transgenic mouse expressing human dystrophin), of 24 AOs of the phosphorodiamidate morpholino oligomer (PMO) chemistry designed to target exon 53 of the DMD gene, skipping of which could be potentially applicable to 8% of patients.
The Republican effort on the absentees, by comparison, was methodical and unrelenting.
Because of methodical differences, a direct comparison of impairments reported in different studies is difficult.
From a methodical point of view, comparison of A-GI and M-GI revealed differences in the mean value of the GI (data not shown).
At the cost of reducing the power of this analysis we wanted to make sure we did not introduce a methodical bias in our comparisons, therefore, the TP53 mutation data for luminal-J and luminal-H tumors were not combined.
Usage of this uniform methodical platform was chosen to generate data allowing for direct comparison between different organs, and hereby to identify neoplasms in which CAR expression might be of importance during malignant progression and the ones where it is not.
The most likely explanation for these differences is that the current study involved a more methodical evaluation, which had higher sensitivity for revealing neurobehavioural problems in comparison with the majority of prior studies conducted by investigators specializing in genetics or metabolic disease.
Make the methods for identifying specific genes more explicitly methodical.
The punitive demolitions add to the anger but pale in comparison to urban policies whose violence is more sanitized and methodical: Jerusalem has razed more than 3,000 Palestinian homes since 2000.
Consistent and methodical presentation of results will accelerate this success, allowing head-to-head comparisons that will facilitate adoption of the AP as a standard therapy for type 1 diabetes.
