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A simple, accurate, precise and sensitive high-performance liquid chromatographic (HPLC) method with ultraviolet detection was developed to quantificate lamivudine (3-TC) in human plasma samples from bioequivalence studies.
To allow such evaluations and to provide a general, sensitive, rapid and simple method for the analysis of compounds containing the 1,5-diaryl-3-oxo-pentadienyl scaffold, we developed an HPLC method with ultraviolet detection for their detection in various biological matrices of a relevant preclinical species, i.e. the rat.
Ionic liquid 1-butyl-3-methylimidazolium bromide-methanol-based ultrasonic-assisted extraction (ILUAE) was used to extract tilianin and acacetin from the aerial parts of Agastache rugose (A. rugose), and simultaneously determined by reversed phase high performance liquid chromatographic (RP-HPLC) method with ultraviolet detection (RP-HPLC-UV).
Water concentrations of florfenicol were determined using a HPLC method with ultraviolet (UV) detection.
Paclitaxel concentrations in urine were determined using a validated HPLC method with ultraviolet (UV) detection (Huizing et al, 1995).
TMZ concentrations in plasma and normal brain microdialysate samples were determined using a validated reversed-phase high-performance liquid chromatography method with ultraviolet detection.
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Few methods reported the quantitation of FEX in pharmaceutical dosage forms using spectrophotometric methods [10], LC methods with ultraviolet detection [11 13], and capillary electrophoresis [14, 15].
Pantoprazole concentration in plasma was determined by a validated high-performance liquid chromatography method (HPLC) with ultraviolet detection following solid phase extraction [ 11].
Feed samples from the Finnish national feed control programme and suspected carry-over samples from a feed manufacturer were analysed in parallel with an existing liquid chromatography method coupled with ultraviolet detection.
Plasma concentrations of antiretroviral drugs were assessed by validated chromatographic methods coupled with ultraviolet light detectors (atazanavir, darunavir, etravirine, lopinavir, tipranavir) or with triple quadrupole mass spectrometry (efavirenz, maraviroc, nevirapine, raltegravir, amprenavir, tenofovir, ritonavir, indinavir, saquinavir, nelfinavir).
Saliva and plasma VPA and plasma 4-en-VPA determinations were performed by a previously published validated high-performance liquid chromatography method (HPLC) with ultraviolet-visible (UV-Vis) [ 29] with minor modifications.
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