The design method is fulfilled through solving linear matrix inequalities.
Training stops whenever one of the conditions mentioned in Levenberg Marquardt method is fulfilled.
In addition, a necessary condition for this method was fulfilled [ 5]; the existing correlations between all factors used in the imputation model were systematically in the same direction.
All the assumptions for using the ANCOVA methods were fulfilled (reliability of covariates, correlations among covariates, and linear relationship between dependent variable and covariate, and homogeneity of variance as revealed by the Levene's test and the variance ratio, also know as Hartley's Fmax).
Assumptions about parametric methods were fulfilled for K mof tyrosine, tryptophan and alanine transport, but not for V maxof tyrosine, tryptophan and alanine transport (determined using Shapiro-Wilk W test). Significance of the difference in K mfor tyrosine, tryptophan and alanine transport between children with ADHD and the comparison group was analysed using the Student's unpaired t-test.
The three parts of the genetic algorithm such as reproduction, mutation, and crossover are employed and some variations in the methods are fulfilled so that a better performance is gained.
A partial validation was executed and all requirements for acceptance, as defined in the FDA and EMA guidelines on Bioanalytical Method Validation [ 17, 18] were fulfilled.
A partial validation was executed and all requirements for acceptance, as defined in the FDA and EMA guidelines on bioanalytical method validation [ 25, 26] were fulfilled.
All objectives were fulfilled.
All requirements were fulfilled satisfactorily.
