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With this method, we probe a central hypothesis of passive microrheology, a field premised on the idea that the statistics of particle trajectories can reveal fundamental information about their surrounding fluid environment.
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Using N-edited NMR methods, we probed the binding of NH4+ to one of the potassium binding sites of HDAC8 and to two potassium binding sites of the bacterial Hsp70 homologue DnaK.
Using this method, we could thus probe immobilised Protein A ligand directly on agarose beads using ATR-FTIR spectroscopy for the first time.
In our new IQRray method, we transform all probe signal values into ranks and subsequently compute the average rank of probes that belong to the same probe set.
Apart from any underlying biological differences, our sampling method was also explicitly biased: we probed our libraries with female cDNA and sequenced non-hybridizing clones in order to enrich our ESTs for male-specific transcripts.
Using the MAS 5.0 gene detection method, we filtered those probe sets that were consistently called "present" in all O157 H7 strains yet were called "absent" in all non-O157 H7 non-O157 H7
Compared with the two-probe method, we believe that the four-probe measurement can further reveal the intrinsic electronic transport properties of the nanowires.
Using a linear model fitting method, we found 9,982 probes that were significantly different between DS and control samples after Benjamini-Hochberg correction.
Using this method, we designed oligonucleotide probes to over 17,000 distinct rhesus/human gene orthologs and increased by four-fold the number of available genes relative to our first-generation expressed sequence tag (EST -derived array.
To demonstrate the usefulness of this method, we introduced this FRET probe into HeLa cells by both transient and stable transfection.
In free probe method, we were clearly identified a melting peak at 81°C corresponds to non-Beijing and a melting peak at 88°C corresponds to Beijing genotype.
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