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Using our modified library generation method, we generated genome-wide DNA methylomes for human sperm, oocytes, 8-cell embryos, morula, ICM, and 6-week embryos as well as the full-term placenta at single-base resolution (Supplementary Table S1).
Herein, using our modified MethylC-Seq library generation method and published post-bisulphite adapter-tagging (PBAT) method, we generated genome-wide DNA methylomes of human gametes and early embryos at single-base resolution and compared them with mouse methylomes.
To demonstrate our method, we generated multicolor 3D reconstructions of several proteins within the human centriole, which revealed their relative locations, dimensions and orientations.
In order to represent some qualitative results about the target orientation dependency of proposed method, we generated a new target shape in Figure 9.
In order to investigate the effect of channel memory for a given ADIR filter memory on the performance of the proposed method, we generated channels with longer impulse responses than that of h a (n), nevertheless, we made sure that these channels have exactly the same spectral characteristics or eigenvalue spread with h a (n).
Using this method we generated 1000 permuted CNV region sets.
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Using FRAGFOLD, a fragment-assembly protein structure prediction method, we generate raw ensembles of proteins43,44,45.
Using the liquid quenching method we generate amorphous carbons at different densities, and subsequently anneal at high temperature.
(14) For each method, we generate size n=300,m=1,000 samples.
For each method, we generate size n=300,m=1,000 samples.
With this method we generate two-photon absorption (TPA) and self-phase modulation images of gold nanostars in biological samples.
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