However, just like any other statistical analysis where you could have multiple approaches to consider (e.g., different multiple comparisons procedures or different kernel methods), we advocate that the analyst consider each of the different dimension reduction procedures and then proceed to use various metrics and diagnostics to determine the best results.
However, limitations with each technique make reliance on any single detection method unwise, and we advocate using at least two of these complementary techniques in any analysis of cartilage PCD.
In the absence of study-specific estimates, we advocate the likelihood-based method with a sensitivity analysis for the correlation parameter.
Research has shown the technical problems when scanning small children based on inconsistency in limb positioning and location of the region of interest [ 35], we advocated the method introduced by Beck et al. when evaluating FN width [ 12].
Method one-step is the method advocated in this paper, method ped uses the pedigree based relationship matrix, and method two-step is the genomic prediction method using only genotyped animals (note that parameter estimates for this method cannot be compared to parameter estimates from the other two methods).
In our view however, both methods are complementary and we therefore advocate a joint use both in case of assessing the optimal set of barcodes and in case of actual species assignment tests by barcoding.
To measure cortical folding patterns for each of the several thousands of vertices across the entire cortical surface, we used the method advocated by Schaer et al. (2008) on the basis of an index originally proposed by Zilles et al. (1988).
This method is similar to the method advocated by Van Loenon et al. who measured the labial surface curvature of the maxillary central incisor and canine [11].
Finally, we demonstrated the effectiveness and limitations of this method and advocated a possible mechanism to prevent intervertebral disc degeneration in a rabbit model.
