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Both validation and PCR measures were combined into groups of similar measures (accuracy, efficiency and practicability) and then aggregated to an indicator of method validity, based on an implementation of the fuzzy-logic-based principle for method validation (software program AMPE [ 27]) and using the design and settings described in Bellocchi et al. [ 28].
Mixing sequence as well as method validity was investigated by numerical simulation.
Limits of detection (LOD) and of quantification (LOQ) are the most important values that researchers look for when considering method validity.
Modeling of design spaces regarding to method robustness fulfils quality by design essence of ensuring method validity throughout the design space.
Results for air firing support method validity by suggesting the common practice in control; keeping power, flue gas O2 and primary air/fuel feed ratio constant.
Reliable values for method validity of organochlorine pesticides determination were investigated, in water by solid phase extraction and in sediment by Soxhlet extraction, followed by gas chromatography equipped with an electron capture detector.
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Simulations and real-world testing in various scenarios confirm the methods validity.
Moreover, to check the methods' validity, dosage forms [Napilac capsules (200 mg ETD per capsule) and Etodine capsules (300 mg ETD per capsule)] were tested for possible interference with the standard addition method (Table 4).
The additions relate to the use of biomarkers in epidemiological studies, concerning collection, handling and storage of biological samples; laboratory methods, validity and reliability of biomarkers; specificities of study design; and ethical considerations.
Methods: Validity and reliability were tested by comparing neurologic examination scores obtained using our wireless system, which transmits video of a patient from a moving ambulance to desktop computers, with those obtained using the National Institute of Neurological Disorders and Stroke training videotape.
See Supplementary Data for details on analytic methods, validity, and reproducibility of these measures.
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