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The first method uses cross-coupling resonators topology.
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To choose τ, the method uses a cross-validation procedure.
Method & Results: 18F-labeled 4-iodophenyl substituted BODIPY was first prepared by the SnCl4-assisted 18F-19F isotopic exchange method 50-700%).4 This radiolabeled moiety was subsequently conjugated in high yield to the C17α-position of estradiol and androgen derivatives under Sonogashira cross coupling reaction conditions using Pd-catalyst, base and CuI.
The method uses k-fold cross validation.
We developed a novel GREACE method using "Mutagenesis coupled-with Selection" as core principle.
Urea was measured with end point method using the couple urease glutamate dehydrogenase (GLDH) enzyme system.
Of the methods that use cross-validation Methods 4 and 6 were often the best.
This method uses a genetic algorithm approach for variable selection coupled to a MLHD functions classifier.
Several different derivatives containing a 9-aryl group were designed and synthesized using Suzuki Miyaura cross-coupling and Ullmann coupling reactions.
Insulin-loaded chitosan microspheres were engineered by emulsion cross-linking method using glutaraldehyde as cross-linker.
In an extension of this method, an iterative cross-coupling protocol was developed for the preparation of (oligo)deoxypropionates.
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