Sentence examples for method to phase from inspiring English sources

We find that our method outperforms existing methods in terms of both speed and accuracy for large data sets with thousands of individuals and densely spaced genetic markers, and we use our method to phase a real data set of 3,002 individuals genotyped for 490,032 markers in 3.1 days of computing time, with 99% of masked alleles imputed correctly.

Kong et al. [ 11] presented a method to phase and impute long haplotype blocks.

To our knowledge, targeted HaploSeq is the first method to phase the MHC and KIR loci into a single haplotype structure.

We now apply the inverse method to phase data that was acquired from a fixed MTC cell plated on glass bottom dishes.

Finally, we apply our inverse method to phase data acquired from light that was reflected from stress fibers and focal adhesions on the ventral plasma membrane, which lies in apposition to the coverslip-buffer interface.

Methods to phase rare variants are being developed, 5 and as more sequence data becomes available then LD relationships between variants will become better understood, and it may be possible to assign even quite rare variants to known haplotypes.

Use of such databases in combination with methods to phase de novo mutations and haplotypes resulting from recent recombinations could both permit increased haplotype quality and reduce the need for genetic and molecular haplotyping in patients from these populations.

It makes the proposed method less sensitive to phase changes.

Subsequently, we demonstrate that the inverse method as applied to phase data collected from the sphere is consistent with the solution of the forward problem.

We developed a method to detect phased KIR gene-content haplotypes based on PCR sequencing of amplicons.

Since extension of the above method to a phased 2-SNP haplotype is equivalent to extending the method to a candidate locus with four alleles, we consider those two scenarios together.