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Linear regression analysis between two variables was done using a simple regression method, the significance of which was quantified by analysis of variance (ANOVA).

According to the Bonferroni correction method, the significance level for the gene-based tests was 2.3×10−6 for each BP measure.

To evaluate sensitivity of our method, the significance level of the differences in the allele frequencies between the two pooled samples with the closest allele frequencies (Table 3) was assessed by the Kolmogorov-Smirnov test.

Researchers just need to define the analysis parameters, such as the covariates to be used in the ANOVA/MANOVA, the FDR correction method, the significance threshold and the minimum difference between mean methylation values between the groups under investigation.

Aside from p-values generated using Fisher's method, the significance of genes shown in Figures 2A and 2B was confirmed by a second method, in which simulation was used to generate null distributions for a test statistic equal to the number of significant results across all tissue types (assuming random association of differential expression patterns among tissues) (P < 0.001 for each gene).

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As for statistical methods, the significance and independence of explanatory variables should be identified in advance for the reliability of statistics.

NHT, JK, ES and GT revised the manuscript critically related to the adequateness of the methods, the significance of the results and the appropriateness of the interpretation of the results.

It is important to note the difference between the DeLong et al. method and the significance testing methods investigated in the previous section for comparing nested models.

An unnamed thirteenth-century Latin manuscript, now held in the library of Trinity College, Cambridge, sets out the method and the significance of the act.

10000 samples of sizes n = 30, 20, 30 are generated for each method at the significance level 0.05.

The ANOVA method with the significance level of 0.05 and 0.025 assess the impact of SUAR during this course accomplished at a university in the south of Mexico City.

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