Sentence examples for method the rationale from inspiring English sources

For this method, the rationale is that drugs with similar gene expression patterns are likely to share common target proteins.

In this method, the rationale for homology assessment is accounting for the fact that secondary structure is functionally constrained in ribosomal RNA.

As pointed out in Materials and methods, the rationale for having a normal group was not to make direct comparisons with patients but instead to generate normative mass-normalised QF MVC results from which patients could arbitrarily be stratified as "weak" or "not weak".

To address this problem we developed a new method, applying the rationale of multiple subpial transection (MST) to the hippocampus.

Therefore with this study we provide a versatile method and the rationale for controlling, at the atomic level, the nature of the interface of graphene/metal oxide nanocomposites.

The RIM method follows the rationale of using real observable outcomes to derive the index and employs two statistical procedures: K-means cluster analysis and discriminant analysis (Li et al. 2005; Li 2011; Lam et al. 2015a, b).

Using the meta-ethnographic approach demands consideration of the suitability of the method and the rationale for using it.

These results, combined with the minimally invasive nature of the delivery method, support the rationale and utility of this approach for patients with ALS.

In using Taverna as a software tool and depositing the workflows in the repository myexperiment.org, we have attempted to make the method and the rationale transparent to users, thus facilitating its retrieval, reuse and reproduction by other independent scientists [ 19].

We next compared an animal's preference for sucrose vs sucralose plus optogenetic activation of MCH neurons (see 'Materials and methods' for the rationale of concentrations chosen).

The effect of different standard preparation conditions was assessed by analysis of z-scores for estimated concentration, calculated as described below (see Methods, where the rationale for z-scoring is also presented).