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In the Bayesian method, the analyses were conducted using MrBayes v3.1 [ 55].
Because the proportional hazards assumption was not met for sex, age group, TKR type, and fixation method, the analyses were run for time intervals ≤ 3.6 years and > 3.6 years (using the median length of follow-up as cut-off point).
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As explained in the Methods, the analyses initially focused on effects related to task switching.
Methods: The analyses were performed by caspase assay, flow cytometry, Western blotting, immunoprecipitation and fluorescent microscopy.
Machine learning and optimization methods are important methods for the analyses.
The latter method uses competing risk methods in the analyses.
Simulation examples are demonstrated to show the effectiveness of the proposed method and the analyses.
The experimental set-up and the method of the analyses are introduced in Sect. 4 more in detail.
For ease of presentation and interpretation, we used the median split method for the analyses presented here.
JV developed the method, performed the analyses, and wrote the paper.
ZDZ implemented the method, performed the analyses, and drafted the manuscript.
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