While ECL technology platform offered many advantages over traditional solid-phase ELISA methods, reliance on a single (or limited) vendor source became a significant concern within the biopharmaceutical industry especially for immunogenicity assays that need to be implemented over a period of many years in support of a single drug development program.
The proponents of "deep history" seek to upend the discipline's most precious precept and method: the reliance on the written record of the past.
One limitation is the method's reliance on self-observation by providers, which may be prone to error.
An important disadvantage of the logistic regression method is reliance on an observed scale score, which may not be an adequate matching variable, particularly for short scales [ 53, 62].
It shows that by using the novel fluorescence normalization method and reliance on the more selected data points fluorescence ratio analysis, significant improvement in precision and repeatability was demonstrated in the novel analysis method compared to conventional method although the proposed strategy does not claim to completely replace the conventional method.
Our results represent a marked improvement an order of magnitude greater than reported by others for injected doses administered by other delivery methods, without reliance on an added adjuvant, and with only a single vaccination.
The assay represents an improvement over previous methods in reliance on the direct mass determination of PCR products rather than on an indirect analysis, where a base-extended or fluorescent report tag is interpreted, both DNA strands being analyzed in parallel, and the ensured specific target amplification simultaneously with mass analysis, providing an additional level of assay precision.
In hydrophobicity assay, two complementary methods, namely, BATH and SAT, were performed to assess bacterial surface hydrophobicity because reliance on one method for this assay is inadequate [ 25].
It is not known whether a breadth of assessment methods are currently being used in UK medical schools, or whether there is reliance on one method over another.
Yet it holds that the rhythm method (that is, reliance on the so-called "safe" period) is acceptable.
