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The reason is that this method provides estimates in closed form while a grid-search is needed with MUSIC.
The HQRPLN method provides estimates closer to the true values as compared to the Chambers et al. (2014) method, and the Machados and Santos Silva (2005) method, which tends to overestimate β1.
For the temporal method, at least two samples are required, preferably separated by multiple generations, while the LD method provides estimates based on a single sample.
In settings for which patient risk can be objectively estimated, this method provides estimates of the risk threshold for individual physicians using only their treatment recommendations.
Figure 4 A shows that the One Biallelic Marker ABC method provides estimates of U within an order of magnitude, for all cases tested.
This statistical method provides estimates of the hazards ratios computed by the Cox model fitted on overlapping subpopulations of patients, where the subpopulations are defined so that they contain patients having increasing age (Bonetti and Gelber, 2000).
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Under these test conditions, the use of the "cone-tainer" method provided estimates of toxicity consistent with those from plants grown in assemblages, and potential interactions between plants were not found to modify the response of macrophytes to atrazine.
The graphical plasma input method and the graphical reference tissue method provided estimates of the binding potential that correlated closely, but differed in magnitude.
The quick method provided estimates that deviated from the pixel count method by <1 day in 7 of 11 trials (64%).
Neither of these methods provides estimates of the lifetime risk of developing cancer.
Overall, predictions produced by the Sun equation, which, although still producing an error larger than the BIS methods, provides estimates closest to the reference dilution values.
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